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Berberine

General Health · Evidence: Moderate · Importance: Avoid Unless Needed

A plant alkaloid studied for blood-glucose and lipid metabolism support.

Educational only — not medical advice. BodEvo summarizes research cautiously and labels estimates as estimates. Talk to a physician or registered dietitian before starting any supplement, diet, or training program.

What the evidence says

Several trials suggest effects on fasting glucose and lipids, but quality varies and interaction/safety considerations are significant. Treat as clinician-guided, not casual.

Typical dose & timing

Dose: Studied around 500 mg, 2–3×/day with meals; this is a metabolically active compound — use only with clinician guidance.

Timing: With meals to improve tolerance.

Role in a stack

Not a general wellness add-on; a targeted compound best used under medical supervision.

Redundancy check: Do not combine with other glucose-lowering supplements/medications without clinician oversight.

Cautions & safety

Common GI side effects. Meaningful drug interactions (it inhibits CYP enzymes) and can lower blood sugar — risky with diabetes medications. Avoid in pregnancy/breastfeeding.

Acts more like a metabolic agent than a casual supplement. Educational only — not medical advice; consult a clinician before use.

Best for

blood-sugar/lipid metabolism interest (with clinician oversight)

Use it in the app: open the Supplement Library and Stack Builder — free, local-first, no account required.